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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are intended solely for research and laboratory use. These products are not intended for human or animal consumption. They are not medicines or drugs and have not been evaluated or approved by the FDA to diagnose, treat, cure, or prevent any disease or medical condition. Any form of bodily introduction is strictly prohibited by law.
PNC-27 30mg is a chimeric research peptide explored for its potent, selective cytotoxicity against malignant cells. Engineered from the HDM-2-binding domain of p53 fused to a cell-penetrating leader sequence, PNC-27 disrupts tumor-cell membranes while leaving healthy cells largely unharmed. Synthesized from premium raw materials and rigorously purified, our PNC-27 offers exceptional consistency and reliability for advanced oncological investigations.
Manufactured under stringent GMP-compliant conditions to maximize purity and bioactivity.
Each lot is subjected to comprehensive HPLC and mass-spectrometry analysis for quality assurance.
Supplied as a lyophilized powder to preserve structural integrity during storage and transport.
Elucidating mechanisms of HDM-2 interaction and membrane pore formation in tumor cells.
Assessing selective cytotoxicity and necrosis induction across diverse cancer lines.
Investigating synergistic potential with existing chemotherapeutic agents.
Material Safety Data Sheet (MSDS): Coming Soon.
Handling and Storage Instructions: Coming Soon.
PNC-27 30mg provides researchers with a precise tool to interrogate targeted anti-cancer strategies, paving the way for deeper insights into tumor-selective therapies.
| CAS No. | 1159861-00-3 |
|---|---|
| Purity | ≥99% |
| Sequence | Pro-Pro-Leu-Ser-Gln-Glu-Thr-Phe-Ser-Asp-Leu-Trp-Lys-Leu-Leu-Lys-Lys-Trp-Lys-Met-Arg-Arg-Asn-Gln-Phe-Trp-Val-Lys-Val-Gln-Arg-Gly |
| Molecular Formula | C188H293N53O44S |
| Molecular Weight | 4031.73 g/mol |
| Applications | Oncology studies, tumor necrosis assays, HDM-2 binding research, selective anti-cancer mechanisms |
| Synthesis | Solid-phase synthesis |
| Solubility | Soluble in water or 1% acetic acid |
| Stability & Storage | Stable for up to 24 months at -20°C. After reconstitution, may be stored at 4°C for up to 4 weeks or at -20°C for up to 6 months. |
| Appearance | White lyophilized powder |
| Shipping Conditions | Shipped at ambient temperature; once received, store at -20°C |
| Regulatory/Compliance | Manufactured in a facility that adheres to cGMP guidelines |
| Safety Information | Refer to provided MSDS |
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