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Laboratory Research Material
IGF-1 LR3
1 mg per vial · Lyophilized powder
Laboratory Research Material
IGF-1 LR3 1 mg per vial
$89.99
- Compound
- IGF-1 LR3
- Amount per vial
- 1 mg
- Form
- Lyophilized powder
- Packaging
- 1 × 3 mL vial, boxed
- Shipping
- 2 business daysEstimated transitFree
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Important
Research Use Notice
All articles and product information provided on this website are for informational and educational purposes only. The products offered on this website are intended solely for research and laboratory use. These products are not intended for human or animal consumption. They are not medicines or drugs and have not been evaluated or approved by the FDA to diagnose, treat, cure, or prevent any disease or medical condition. Do not administer these products to humans or animals.
Product Documentation
Details, specifications, and documents
Description
IGF-1 LR3 1 mg
Buy IGF-1 LR3 1 mg for laboratory research, supplied as lyophilized powder in one boxed 3 mL vial.
IGF-1 LR3 is a modified insulin-like growth factor used in laboratory research on growth-factor interactions and analytical identification.
What distinguishes the LR3 analog?
The reference Long Arg3-IGF-I structure has an extension of 13 amino acids at the N-terminus and an arginine substitution at position 3 of the IGF-I portion. These changes distinguish it from native IGF-I, R3-IGF-I without the extension, and the truncated DES(1-3) analog. Keep the complete analog name in the method and purchase record.
In Francis and colleagues’ original comparison, the modified proteins interacted differently with IGF-binding proteins. Long Arg3-IGF-I produced stronger responses than native IGF-I in some cell models, while the comparison reversed in fibroblasts that lacked detectable secreted binding proteins. That distinction matters when selecting a reagent: activity depends on the experimental system, not simply the presence of the LR3 name.
Analytical identity and sample condition
Mongongu and colleagues used antibody-based purification followed by nano-liquid chromatography and high-resolution mass spectrometry to distinguish IGF-I analogs. Their work evaluated recovery and matrix effects in fortified serum and identified oxidized forms and N-terminal degradation products.
These observations show why an intact target, related forms and the sample matrix can all matter in analytical method development. They describe the preparations in that study; they do not establish the identity or activity of a separate commercial lot.
Review the material records
Use Documents for the available product files and review the applicable batch report alongside the vial label. Identity, chromatographic purity, measured content and biological activity answer different questions. Check which measurements a report actually contains before using it to support a method.
The labeled 1 mg amount is a material quantity, not a solution concentration. The 3 mL vial specifies the container capacity. Match the supplied form and material-specific handling guidance to your laboratory’s preparation and storage conditions. Current price and availability remain in the purchase section.
Additional information
| CAS No. | 946870-92-4 |
|---|---|
| Purity | ≥99% |
| Synthesis | Solid-phase synthesis |
| Format | Lyophilized powder |
| Solubility | Soluble in water or 1% acetic acid |
| Stability & Storage | Stable for up to 24 months at -20°C. |
| Applications | Cell growth and differentiation studies, muscle development and aging research, therapeutic research in muscle wasting and metabolic disorders |
| Appearance | White lyophilized powder |
| Shipping Conditions | Shipped at ambient temperature; once received, store at -20°C |
| Regulatory/Compliance | Manufactured in a facility that adheres to cGMP guidelines |
| Safety Information | Refer to provided MSDS |
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