Important

Research Use Notice

All articles and product information provided on this website are for informational and educational purposes only. The products offered on this website are intended solely for research and laboratory use. These products are not intended for human or animal consumption. They are not medicines or drugs and have not been evaluated or approved by the FDA to diagnose, treat, cure, or prevent any disease or medical condition. Do not administer these products to humans or animals.

Product Documentation

Details, specifications, and documents

Description

Thymogen 20 mg research peptide

Buy Thymogen 20 mg for laboratory research, supplied as lyophilized powder in one boxed 3 mL vial.

Thymogen is a dipeptide associated with the reference sequence Glu-Trp, also written EW.

Use the complete material name when comparing protocols. Thymogen, Thymosin Alpha-1 and the Thymalin preparation are different materials; their findings and specifications should not be combined. The vial’s 20 mg label identifies a material amount, not a prepared solution concentration.

Thymogen in THP-1 cell experiments

Avolio and colleagues’ 2022 study compared Thymogen with four other peptide preparations in the human leukemia-derived THP-1 cell line. The work included monocytes and cells differentiated with PMA into a macrophage-like state.

In differentiated cells stimulated with lipopolysaccharide (LPS), the researchers reported reduced TNF and IL-6 release with all five preparations, including Thymogen. They also examined kinase phosphorylation and proliferative responses. These are specific laboratory readouts under defined culture conditions.

Keep the cell state attached to the result: a response in differentiated, LPS-stimulated cells is not automatically the same as a response in undifferentiated monocytes. Likewise, a finding reported only for another peptide in the comparison should not be assigned to Thymogen. The paper provides experimental context rather than a biological-activity certificate for a commercial lot.

Check the material records

The Documents tab provides available product files. If you need a batch report for your experiment, request it for the supplied lot and match its name and presentation to the vial. Confirm the supplied chemical form and any sequence details required to reproduce a study.

Separate the analytical questions when reading a certificate: an identity result, HPLC purity and measured content are different measurements. A purity percentage alone does not predict a cytokine response in cell culture.

Use the documented storage and handling requirements for this material. Request any missing specification your protocol depends on before preparing an experiment.

Additional information

CAS No.

38101-59-6

Purity

≥99%

Sequence

Glu-Trp

Molecular Formula

C16H19N3O5

Molecular Weight

333.34 g/mol

Applications

Immune modulation research, inflammation studies, tissue repair and recovery

Synthesis

Solid-phase synthesis

Format

Lyophilized powder

Solubility

Soluble in water or 1% acetic acid

Stability & Storage

Stable for up to 24 months at -20°C.

Appearance

White lyophilized powder

Safety Information

Refer to provided MSDS

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