AICAR 50 mg: research material

Buy AICAR 50 mg for laboratory research, supplied as lyophilized powder in one boxed 3 mL vial.

AICAR is a nucleoside research compound used in studies of AMP-activated protein kinase (AMPK) and cellular energy metabolism. It is a small molecule, not a peptide.

Choose the material and presentation

The riboside and its phosphorylated product, ZMP, are different chemical forms. Some publications use the AICAR abbreviation for the nucleotide, so the abbreviation alone can be ambiguous. Check the full chemical identity in the method before comparing a cell experiment with a purified-enzyme assay.

This 50 mg presentation states an amount of dry material. It is not a solution concentration or an assay-ready preparation.

AICAR, ZMP and AMPK research

Hénin and colleagues examined AMPK purified from rat liver. ZMP stimulated the enzyme, but its apparent affinity was lower than AMP’s and depended on the ATP concentration used in the assay.

The study also distinguishes the AICA riboside added to cells from ZMP formed through phosphorylation by adenosine kinase. That conversion matters when interpreting experiments: a response in intact cells and a response to ZMP in an isolated enzyme system are different observations. The paper does not establish a universal response across cell types.

Original study

Product records and batch reports

The product documentation section holds available batch reports and product files. Review the reported chemical identity, labeled amount and relevant analytical results together. Do not substitute a peptide sequence, or a different phosphorylated form’s formula, for the identity of this nucleoside material.