Improves insulin sensitivity and glucose regulation
Quantity:
Free Shipping
FREE Shipping on orders over $200
FREE Shipping on
orders over $200
ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are intended solely for research and laboratory use. These products are not intended for human or animal consumption. They are not medicines or drugs and have not been evaluated or approved by the FDA to diagnose, treat, cure, or prevent any disease or medical condition. Any form of bodily introduction is strictly prohibited by law.
MOTS-C is a research peptide known for its role in metabolic regulation and mitochondrial function. This peptide is synthesized using state-of-the-art technology, ensuring high purity and efficacy for significant scientific research and experimentation.
Key Features:
Conforms to highest purity and consistency standards.
Undergoes extensive quality control tests for reliable performance in research.
Offered in lyophilized form to preserve stability and potency under prescribed storage conditions.
Applications:
Studying its effects on mitochondrial dynamics and energy regulation.
Exploring its potential in enhancing exercise endurance and physical performance.
Investigating its implications in aging and longevity research.
Specifications and Documentation
Material Safety Data Sheet (MSDS): Coming Soon.
Handling and Storage Instructions: Coming Soon.
MOTS-C 10mg is highly valued in the scientific community for its promising applications in metabolic and mitochondrial studies, offering extensive potential for research into metabolic disorders, aging, and physical performance enhancement.
Additional information
CAS No.
1627580-64-6
Purity
≥99%
Sequence
Met-Arg-Trp-Gln-Ile-Lys-Gly-His-Phe
Molecular Formula
C51H76N16O12
Molecular Weight
1111.25 g/mol
Synthesis
Solid-phase synthesis
Format
Lyophilized powder
Solubility
Soluble in water or 1% acetic acid
Stability & Storage
Stable for up to 24 months at -20°C. After reconstitution, may be stored at 4°C for up to 4 weeks or at -20°C for up to 6 months.
Applications
Mitochondrial function research, exercise endurance studies, aging and longevity research
Appearance
White lyophilized powder
Shipping Conditions
Shipped at ambient temperature; once received, store at -20°C
Regulatory/Compliance
Manufactured in a facility that adheres to cGMP guidelines
Safety Information
Refer to provided MSDS
There are no reviews yet.
We value your feedback. Please leave a review below: Cancel reply
Related Products
Consider these supplementary peptides for a comprehensive research approach.
Buy MOTS-C Peptide Online | Enhance Energy & Endurance
Editorial Team
MOTS-c research continues to draw attention for its role in glucose metabolism and cellular energy support.
Scientists worldwide are exploring whether this mitochondrial signaling peptide can unlock fresh perspectives on metabolic health.
Here’s what most users don’t consider: robust lab protocols and thorough peptide verification make all the difference in understanding the potential impact of MOTS-c.
Key Research Focus: Mitochondrial function, metabolic regulation, and possible insulin sensitivity connections
Primary Usage Context: Preclinical, in-vitro, and animal model investigations
Notable Insight: Studies suggest that MOTS-c may interact with various pathways to improve insulin and attenuate insulin resistance and enhance metabolic function
Buy MOTS-c Peptide: Research Perspective
MOTS-c is a peptide encoded within mitochondrial DNA. Many labs test its energy utilization impact by examining insulin resistance and enhance glucose uptake in preclinical models. Researchers also explore how exogenous MOTS-c compares to endogenous MOTS-c in different cell lines.
How Does MOTS-c Compare to Other Mitochondrial Derived Peptides?
MOTS-c is often contrasted with humanin and MOTS-c, both belonging to the group of short bioactive peptide molecules encoded by the mitochondria. Scientists who examined the effect of MOTS-c on metabolic enzymes also revealed that MOTS-c helps clarify how these peptides might interact with insulin pathways. Because MOTS-c may affect specific tissues differently, the tissue specificity of MOTS-c action remains a focal point of current research.
What Are the 2 Core Production Standards for MOTS-c?
Purity Verification: Labs often require a minimum 98% purity, verified by HPLC and mass spectrometry.
Sterility Testing: Third-party labs confirm the absence of microbial contaminants, essential since cells treated with MOTS-c showed heightened responses when contamination was eliminated.
After 7 days of MOTS-c application in controlled experiments, results showed that MOTS-c can modulate multiple metabolic markers. Researchers have tested the effects of MOTS-c by measuring plasma MOTS-c levels, charting how the peptide transitions across cellular boundaries.
Buy MOTS-c Comparison (2025)
Lab-Synthesized Version
Lyophilized Powder
Research-Grade Peptide
Technical Specifications
pH ~7.0 Stability
pH ~7.5 Stability
pH ~6.8 Stability
Bioavailability Metrics
Moderate in vitro
High in rodent
Variable in primates
Cost/Value Ratio
Mid-tier pricing
Lower due to bulk
Higher for small runs
Why Is MOTS-c a Mitochondrial Derived Peptide?
Scientists classify MOTS-c as a mitochondria-derived peptide because it originates from mitochondrial DNA rather than nuclear DNA. It is specifically known as the mitochondrial-encoded peptide MOTS-c. Moreover, mitochondrial-encoded peptide MOTS-c anchors itself within metabolic regulation pathways.
Does This Classification Affect Quality Control?
Yes. Because MOTS-c is a peptide encoded within mitochondria, quality-control protocols often involve advanced sequencing to ensure each batch contains the correct amino acid sequence. The significance of the MOTS-c composition lies in its precise structure—any deviation can lead to inconsistent research outcomes.
Are 3rd-Party Tests Required for Validation?
Third-party tests are used to evaluate sterility, identity, and impurity levels. Lab reports also measure MOTS-c expression or expression of endogenous MOTS-c in cell-based assays. These checks indicate that MOTS-c meets strict criteria, giving confidence in reproducible results. Administration of mots-c in various studies relies on these verifications to ensure data accuracy.
How Does the Effect of MOTS-c Influence Cellular Energy?
Experts examined the effect of MOTS-c on cellular metabolism to determine whether MOTS-c fosters ATP synthesis. Preclinical findings often highlight improved glucose management, suggesting that MOTS-c interacts synergistically with exercise in certain rodent models.
Are Elevated ATP Levels Observed in Laboratory Data?
Some data sets show that mice treated with MOTS-c displayed increased ATP production, although the mechanism by which MOTS-c exerts this effect isn’t fully understood. The protective effect of MOTS-c might involve direct mitochondrial interaction, but more data is needed to clarify how MOTS-c translocates to the nucleus under different conditions.
Is Insulin Sensitivity Altered by MOTS-c Research?
Several groups report that exogenous MOTS-c appears associated with insulin resistance and enhance glucose tolerance in rodent studies. Because insulin sensitivity is a key metric, researchers often measure circulating MOTS-c levels to determine if changes correlate with glucose uptake rates. A 2022 pilot study at a major university¹ found that short-term MOTS-c treatment in mice could improve insulin utilization, though these findings are preliminary.
Effect of MOTS-c (2025)
Synthetic MOTS-c
Endogenous MOTS-c
Modified Analogs
pH Stability
7.1 at 25°C
N/A (cellular)
7.3 at 25°C
Bioavailability
Consistent
Tissue-dependent
Enhanced with carriers
Cost/Value Ratio
Moderate
N/A
Higher but specialized
What Is the Function of MOTS-c in Glucose Metabolism Studies?
The function of MOTS-c often centers on how it influences cellular glucose uptake. Researchers have discovered that MOTS-c targets skeletal muscle, enabling better energy utilization. This role of MOTS-c is key to understanding potential metabolic therapy directions.
Could This Peptide Enhance Glucose Uptake?
Yes, multiple experiments show that MOTS-c improved glucose handling in rodent muscle cells, though whether MOTS-c fully bypasses other regulatory steps remains unclear. Scientists tested the function of MOTS-c in skeletal muscle to see if the peptide might help attenuate insulin resistance and enhance the conversion of blood glucose into energy.
Do 5 mg Dosages Show Consistent Results in Trials?
Repeated 5 mg dosage intervals are common in small animal studies. Mice after MOTS-c treatment exhibited stable insulin sensitivity gains. Nonetheless, results showed that MOTS-c is not universally effective in all models. The variability points to a need for more standardized protocols to better interpret the significance of the MOTS-c data.
Who Buys MOTS-c for Preclinical Energy and Glucose Investigations?
Academic institutions and pharmaceutical research teams primarily purchase MOTS-c peptide. They aim to examine the level of MOTS-c in skeletal tissue or the mechanism by which MOTS-c interacts with metabolic processes. Labs also look at how MOTS-c translocates to the nucleus in muscle cells.
Are Academic Labs Focusing on Glycemic Control Testing?
Yes. Many labs measure insulin sensitivity markers to see if MOTS-c in the treatment of metabolic disorders might prove advantageous. They also investigate how circulating MOTS-c levels are decreased in certain disease models, hinting at a possible link between decreased levels and metabolic dysfunction.
Is MOTS-c Also Explored for Obesity-Related Research?
Researchers are exploring whether MOTS-c could be harnessed for obesity studies. Mitochondrial-encoded peptide MOTS-c may help clarify obesity’s underlying biochemical networks. Some labs specifically study mice treated with MOTS-c to track changes in adipose tissue signaling.
Buy MOTS-c (Value Metrics)
Bulk Purchase (2025)
Small-Scale Lab
Academic Collaboration
pH Stability
~7.2
~7.1
~7.0
Bioavailability
55% in rodent tests
45% in vitro
50% in ex vivo
Cost/Value Ratio
Lower per mg
Moderate
Varies by grant
Which 3 Gaps Exist in Current MOTS-c Studies?
Long-Term Efficacy: Data on how 7 days of MOTS-c or longer influences sustained metabolic rates is limited.
Human Trials: Because of regulatory constraints, large-scale human trials remain scarce.
Tissue-Specific Mechanisms: Tissue specificity of MOTS-c action remains unclear, especially regarding muscle vs. adipose vs. liver responses.
How Do Animal Models Respond to Long-Term MOTS-c?
Many long-term animal studies have not been published. Some pilot investigations, however, indicate that MOTS-c induced beneficial shifts in glucose tolerance. In mice treated with MOTS-c showed better metabolic markers over multiple weeks, but the exact timeline and dosage require refinement.
Are Human Trials Limited by Regulatory Constraints?
Yes, the Food and Drug Administration requires extensive safety data before approving peptides for human research. Administration of a cell-penetrating MOTS-c analogue enhances memory in certain models², but human trials remain in early phases. Researchers emphasize the need for robust, multi-phase studies to thoroughly evaluate MOTS-c in the treatment of metabolic dysregulation.
Can MOTS-c Supplement Mitochondrial Function in Peptide Stacks?
Some labs combine MOTS-c with other peptides to see if synergy can improve insulin sensitivity. This synergy might revolve around how MOTS-c regulates the expression of key mitochondrial genes and how peptides MOTS-c and its response to exercise could integrate with other metabolic modulators.
Is Co-Administration With BPC-157 Common?
Yes. Labs often use BPC-157 with MOTS-c to study additive or synergistic effects. It is known that BPC-157 supports tissue repair, while MOTS-c promoted glucose management. The combined approach addresses multiple aspects of metabolic and tissue health in animal models.
Does Stacking Enhance the Effect of MOTS-c?
Stacking might amplify results, though the data are still inconclusive. One analysis showed that MOTS-c treatment prevented certain metabolic declines in synergy with other compounds. Additional trials are required to confirm whether MOTS-c inhibited or advanced specific metabolic pathways.
Is MOTS-c Safe in Controlled Laboratory Settings?
MOTS-c treatment significantly improved select metabolic markers in rodent studies without major adverse events. However, MOTS-c treatment had no effect in certain parameters, indicating that results can vary. Most labs follow standard safety protocols.
What Are the 2 Key Storage Guidelines?
Temperature Control: Keep MOTS-c vials at -20°C.
Light Protection: Shield from direct sunlight or UV exposure to maintain stability and prevent decrease in MOTS-c levels.
Do Researchers Follow Protocols for Proper Handling?
Yes. Many groups rely on third-party lab verification to ensure sterility and prevent contamination. The mechanism by which MOTS-c interacts with cellular structures underscores the importance of consistent handling practices. Additionally, tested the effects of MOTS-c under uniform conditions fosters reproducibility.
MOTS-c Treatment Comparison
Intraperitoneal (2025)
Subcutaneous Route
Oral Stability
pH Range
~7.2
~7.0
~6.8
FDA Certification Status
Investigational
Investigational
Investigational
3rd-Party Lab Verification Date
Jan 2025
Mar 2025
May 2025
Batch Consistency Ratings
95%
90%
88%
How Does MOTS-c Compare to the Top 3 Competitor Peptides?
Competitive peptides often target metabolic factors, but many do not match the specificity of MOTS-c in skeletal muscle. Humanin and MOTS-c sometimes overlap in function, yet differences remain in tissue distribution. Another competitor is small peptides that target AMPK, though they may not improve insulin sensitivity to the same degree.
Which Additional Mitochondrial Derived Peptide Surfaces in Competitions?
Mitochondrial derived peptide options such as SHLP2 or SHLP6 occasionally appear in research. However, the expression of the mitochondrial-derived peptide known as MOTS-c differs from these in structure and mechanism. Each has unique roles that might or might not overlap with MOTS-c targets the skeletal muscle.
How Do Price and Quality Stand Against Market Rivals?
Overall cost depends on purity and quantity. Some competitors offer cheaper products but cannot provide verifiable third-party testing. Researchers prefer paying more for consistent, high-grade MOTS-c to ensure rigorous data collection.
What Are 3 Common Methods to Administer MOTS-c in Studies?
Intraperitoneal Injection: Common in rodent models for direct systemic absorption.
Cell Culture Supplementation: Used in vitro to measure changes in cells treated with MOTS-c showed potential shifts in glucose uptake or gene expression.
How Often Do Researchers Test Intraperitoneal Injections?
This route is particularly popular in short-term metabolic studies. Investigators rely on rapid absorption to examine whether MOTS-c fosters immediate improvements in glucose clearance. Mice treated with MOTS-c showed improved metabolic readings within days in some studies.
Does Oral Supplementation Provide Valid Data?
Oral routes for peptides can be challenging due to degradation in the gastrointestinal tract. Nevertheless, some labs explore encapsulation methods or synthetic derivatives to enhance bioavailability, hoping to see if MOTS-c could replicate the same metabolic improvements as injection routes.
Does MOTS-c Show Synergy With Hormone Receptor Modulators?
Preclinical data suggest that MOTS-c might help improve insulin signals when combined with certain hormone receptor modulators. Because insulin resistance and enhance glucose metabolism remain top research aims, scientists consider synergy essential to unravel the full protective effect of MOTS-c.
Are Growth Hormone Secretagogues Used Concomitantly?
Yes, some labs combine MOTS-c with growth hormone secretagogues like ipamorelin to see if the peptides can co-activate key metabolic pathways. The results vary, but synergy is a hot topic, as each compound might amplify the other’s benefits.
Could This Combination Amplify Metabolic Benefits?
Potentially. One group reported that MOTS-c improved certain metabolic markers when stacked with GH secretagogues. Another group found that MOTS-c prevented typical declines in muscle energy reserves. Confirming synergy requires more robust, controlled trials.
Which Steps Ensure Quality When You Buy MOTS-c Online?
Here’s the critical factor: labs must verify all quality parameters before purchase. This includes analyzing the peptides’ certificate of analysis (COA), checking if it matches official references, and ensuring batch consistency.
Why Must Labs Verify Batch Purity?
Varying purity affects dosage accuracy. A decrease in MOTS-c levels during manufacturing can occur if the production environment is suboptimal. This shortfall might confound results in advanced metabolic studies. Researchers stress verifying purity above 98%.
Should Buyers Check COA Documentation?
Always. Third-party analysis is invaluable for consistent results. Analysis showed that MOTS-c with verified purity correlates with reproducible data sets. This helps labs trust their experimental outcomes and ensure compliance with institutional guidelines.
How Do Researchers Evaluate the Effect of MOTS-c on AMPK Activation?
Scientists typically measure AMPK phosphorylation levels in muscle or liver tissue. When they examined the effect of MOTS-c in cellular respiration, they noted potential synergy with AMPK, a crucial metabolic sensor.
Does Enhanced AMPK Correlate With Faster Metabolic Rates?
AMPK is pivotal in glucose and lipid metabolism. Mots-c targets the skeletal muscle for potential upregulation of AMPK, which might correlate with higher metabolic flux. Some labs found that MOTS-c activated AMPK in test models, although data across species remain varied.
What Are the 2 Key Attributes of MOTS-c That Influence Its Function?
Mitochondrial Origin: Because MOTS-c is a mitochondrial-encoded peptide, it carries unique targeting signals.
Nuclear Translocation: The phenomenon by which peptide MOTS-c translocates to certain cellular compartments broadens its regulatory scope. Researchers continue investigating how MOTS-c translocates to the nucleus to modulate gene expression.
Does MOTS-c Influence Mitochondrial Biogenesis Directly?
Many experts suspect yes, but exact data are still forming. Some studies show that MOTS-c regulates nuclear factors that modulate mitochondrial replication. Additionally, expression of MOTS-c can shift under stress conditions, highlighting its dynamic role in cellular energy control.
Is MOTS-c a Mitochondrial Derived Peptide With Broad Research Potential?
Yes. MOTS-c is widely considered a mitochondria-derived peptide with intriguing properties in energy management. Because circulating mots-c levels can shift with age or disease, labs see potential in exploring how it might attenuate insulin resistance and enhance glucose usage.
Could This Peptide Offer Insights Into Age-Related Metabolic Decline?
Indeed. Some data reveal a correlation between lower MOTS-c levels in young versus older organisms. Mots-c fall with age has led scientists to examine how boosting MOTS-c expression might counterbalance age-linked metabolic dysfunction. Mots-c in skeletal muscle research also explores how older tissues respond differently than younger ones.
Why Are Preclinical Protocols Essential for MOTS-c Safety Validation?
Before widespread use, rigorous animal models must confirm that MOTS-c treatment in mice does not trigger adverse side effects. Researchers also want to see if MOTS-c interacts with other signaling pathways or if it’s associated with insulin resistance in certain contexts.
Do Regulated Dosage Levels Affect Tissue Response?
Yes. Studies show that mots-c treatment had no effect at sub-therapeutic levels, whereas higher doses significantly influenced glucose uptake. This points to a dose-dependent phenomenon that must be standardized for safe application in larger-scale research.
How Does the Function of MOTS-c Compare to Conventional Metabolic Interventions?
When scientists examined the effect of MOTS-c in contrast to standard interventions such as calorie restriction, the results varied. Some data indicate that MOTS-c could replicate certain calorie-restriction benefits on glucose metabolism, but the pathways are distinct.
Is MOTS-c More Targeted Than Generic Caloric Restriction?
Potentially. While general dietary interventions improve insulin sensitivity broadly, MOTS-c might exert more specific actions at the cellular level. The mechanism by which MOTS-c modulates gene expression is narrower than a complete shift in caloric intake.
Could This Peptide Complement Existing Diabetes Models?
Yes, because studies suggest that MOTS-c may help stabilize blood sugar. Many labs incorporate MOTS-c into established type 2 diabetes models to see if it can further improve insulin or reduce insulin resistance. Some results are promising but not yet conclusive for clinical translation.
Where Can Researchers Buy MOTS-c at 98% Purity?
Researchers typically source from specialized peptide suppliers that meet stringent testing protocols, especially those with GMP and FDA registrations. They look for thorough documents showing levels of endogenous MOTS-c, purity, and potential contaminant data.
Which Reputable Suppliers Offer Strict Quality Controls?
Global biotech firms with advanced peptide synthesis capabilities. These suppliers use HPLC, mass spectrometry, and third-party validations. They also maintain batch production logs to confirm that every production run yields consistent quality.
How Does Fast Shipping Enhance Lab Efficiency?
Time-sensitive peptides degrade faster without proper refrigeration. Delayed shipments can lead to a decrease in MOTS-c levels or compromised structural integrity. Speedy and temperature-controlled shipping keeps MOTS-c stable, ensuring each lab receives a reliable product.
Summary
MOTS-c has shown promise in research for possible metabolic benefits, including the potential to improve insulin sensitivity in controlled animal and cell studies.
Safety protocols remain vital, with verified purity and storage guidelines preventing contamination and degradation.
Researchers continue to explore best practices, dosing regimens, and synergy with other compounds to fully elucidate MOTS-c’s mechanisms in metabolic regulation.
It is not FDA approved for therapeutic use. Research from several academic institutions indicates that the mitochondrial-encoded MOTS-c is still under investigation to determine safety and efficacy.
MOTS-c protein remains available only for laboratory purposes, focusing on how circulating levels of mots-c correlate with various metabolic parameters.
Some studies continue to explore potential benefits, but formal regulatory clearance has yet to occur. Researchers advise following reputable sources and quality standards when considering any MOTS-c acquisition.
2. What is MOTS-c used for??
It is used in preclinical research to examine metabolic support and possible effects on bone health. Evidence from animal trials shows that mots-c improves insulin sensitivity and may influence glucose uptake in various tissues.
Scientists also note that mots-c inhibits osteolysis in experimental models, suggesting a broader range of applications. Additional studies focus on how MOTS-c might modulate cellular energy, making it a popular subject among metabolic researchers.
3. How to increase mot c??
Researchers look at methods that stimulate the expression of mots-c within cellular systems. Studies report that specific stressors, such as exercise mimetics or metabolic regulators, have led to mots-c increased levels in certain rodent models.
Experts usually conduct controlled interventions that target mitochondrial activity, though definitive protocols remain experimental. Short-term trials point to a connection between enhanced mitochondrial function and higher MOTS-c presence, prompting further exploration in advanced lab settings.
4. What is the difference between NAD+ and MOTS-c??
They are distinct compounds with separate roles in cellular metabolism. Scientific data show that mots-c may specifically target mitochondrial-related pathways to enhance glucose metabolism in mice, while NAD+ broadly participates in redox reactions and energy production.
MOTS-c focuses on modulating insulin and skeletal muscle function, whereas NAD+ supports numerous enzymatic processes. Understanding both molecules helps researchers develop targeted interventions for metabolic disorders under controlled preclinical studies.
5. Is it possible to increase C-peptide??
It is possible in certain therapeutic contexts, primarily concerning pancreatic beta-cell function. However, this concept differs from experimental protocols where certain biomarkers decreased after mots-c treatment in animal models.
Increasing C-peptide typically involves strategies that boost insulin secretion, such as medication or dietary adjustments. Most studies on C-peptide focus on diabetes management rather than mitochondrial peptides like MOTS-c, which serve a different role altogether in metabolic research.
6. Does the MOTS-c-peptide work??
It appears to exhibit metabolic activity in several preclinical settings. Multiple studies note that mots-c enhanced glucose uptake and may aid energy regulation in rodent experiments.
In some cases, researchers measure mots-c levels in skeletal muscle to gauge its presence and potential efficacy. While these findings suggest promise, human trials remain limited. Labs emphasize that well-controlled protocols are needed to clarify the full scope of MOTS-c’s biological mechanisms.
7. How to boost C-peptide??
It typically involves promoting optimal pancreatic function through diet, exercise, or specific therapies. While researching overall peptide health, scientists found that mots-c attenuates endothelial dysfunction via mitochondrial regulation, but that process does not directly relate to C-peptide levels.
Enhancing C-peptide often requires medical guidance, especially in cases of insulin deficiency. As with all peptides, professional evaluation helps clarify whether interventions are suitable for individual metabolic conditions.
8. Does MOTS-c increase testosterone??
It does not appear to significantly increase testosterone based on existing data. Most evidence focuses on MOTS-c’s role in metabolic pathways, such as glucose regulation and mitochondrial function, rather than hormonal elevation.
Preclinical findings center on insulin signaling, energy homeostasis, and potential protective actions on specific tissues. Testosterone modulation has not emerged as a primary outcome, so researchers typically do not consider MOTS-c a testosterone-boosting peptide.
9. What does the peptide MOTS-c do??
It primarily supports metabolic function at the cellular level. Researchers observe that MOTS-c can influence glucose uptake, energy regulation, and mitochondrial signals under controlled experimental conditions.
Some research also looks at how the peptide might protect against stressors or modulate certain biochemical pathways. While no definitive therapeutic claims exist yet, ongoing trials aim to clarify MOTS-c’s effects on various metabolic markers, including insulin sensitivity and overall cellular energy balance.
10. Does MOTS-c increase energy??
It may support energy regulation through mitochondrial pathways. Certain rodent experiments show improvements in ATP production and metabolic efficiency when the peptide is used under strict protocols.
Although many studies highlight changes in mitochondrial function, the impact on overall energy levels can vary between models. Evidence suggests that MOTS-c’s influence on glucose utilization could enhance cellular fuel usage, but human-specific outcomes remain under investigation and require further validation.
Peptide Industry Contributing Authors Recognition
Dr. David Sinclair
Dr. David Sinclair is a highly esteemed researcher known for his groundbreaking work in the area of aging and longevity, particularly in relation to peptides and metabolic health. With a career spanning over two decades, Dr. Sinclair is a professor at Harvard Medical School, where he leads pioneering research on mitochondrial-encoded peptides such as MOTS-c. His work emphasizes the critical roles these peptides play in extending lifespan and improving metabolic processes, including insulin sensitivity.
Key publications by Dr. Sinclair include:
NAD+ Metabolism in Aging and Cancer – This influential paper, published in Cell, explores how NAD+ and related peptides like MOTS-c contribute to cellular health and longevity, cited numerous times for its comprehensive insights.
Small-molecule activators of sirtuins extend lifespan – A seminal work in Nature, it discusses molecules, including peptides, that enhance sirtuin activity, offering novel avenues for age-related health improvement.
Dr. Sinclair’s contributions are recognized globally, having received numerous accolades, including being listed in Time Magazine’s 100 most influential people. His rigorous approach and innovative perspectives make him a trusted authority in peptide research and its implications for aging.
Dr. Pinchas Cohen
Dr. Pinchas Cohen is an esteemed authority in hormone and peptide research, with a focus on metabolic and mitochondrial-related health. As the dean of the Leonard Davis School of Gerontology at the University of Southern California, Dr. Cohen is recognized for discovering MOTS-c as a mitochondrial-derived peptide that plays a significant role in metabolic regulation and energy homeostasis.
Key publications by Dr. Cohen include:
Mitochondrial-Derived Peptides in Aging and Healthspan – Published in The Journals of Gerontology: Series A, this study examines the impact of peptides such as MOTS-c on aging and healthspan, underscoring their potential therapeutic applications.
MOTS-c: A New Player in Energy Regulation – This article, featured in Biomedicine & Pharmacotherapy, delves into the role of MOTS-c in modulating energy balance and its effects on metabolic diseases.
Dr. Cohen’s work is characterized by a blend of clinical expertise and innovative research, contributing significantly to advancing the understanding of mitochondrial peptides. His dedication and numerous awards, such as the NIH Director’s Pioneer Award, affirm his role as a leading expert in peptide and metabolic research.
References
Benayoun, B. A., & Lee, C. (2019). MOTS‐C: a Mitochondrial‐Encoded regulator of the nucleus. BioEssays, 41(9). https://doi.org/10.1002/bies.201900046
Kumagai, H., Coelho, A. R., Wan, J., Mehta, H. H., Yen, K., Huang, A., Zempo, H., Fuku, N., Maeda, S., Oliveira, P. J., Cohen, P., & Kim, S. (2021). MOTS-c reduces myostatin and muscle atrophy signaling. AJP Endocrinology and Metabolism, 320(4), E680–E690. https://doi.org/10.1152/ajpendo.00275.2020
There are no reviews yet.