NAD+ 500 mg: research material

Buy NAD+ 500 mg for laboratory research, supplied as lyophilized powder in one boxed 3 mL vial.

NAD+ is the oxidized form of nicotinamide adenine dinucleotide, a coenzyme used in redox and other enzyme reactions. It is a nucleotide cofactor, not a peptide.

Choose the material and presentation

The plus sign identifies the oxidized cofactor; NADH is its reduced counterpart. NADP-related cofactors have an additional phosphate group. These distinctions matter when an assay specifies a particular cofactor. A precursor used to make NAD+ is also a different starting material from NAD+ itself.

Other presentations: NAD+ 1000 mg.

NAD+ as a research cofactor

SIRT1 uses NAD+ in deacetylation reactions, making it one example of a cofactor-dependent enzyme system. Davenport and colleagues compared crystal structures of the human SIRT1 catalytic domain in open and closed states. The closed complex contained ADP-ribose, an NAD+ hydrolysis product, and a substrate-mimicking peptide. Their biochemical experiments also identified an inhibitory role for a C-terminal regulatory segment. This work explains enzyme organization and regulation; it does not measure cellular uptake of a purchased NAD+ preparation.

Original study

Product records and batch reports

Open the COA and documents tab for the available batch reports and product files. Match the product and lot, then read identity, purity and measured content as separate results.