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LL-37 5mg (CAP-18)

$84.99

(5.0) (20 customer reviews)

Research Studies:

  • Facilitates analysis of hCAP-18 proteolytic cleavage into biologically active LL-37
  • Supports investigation of FPR2-mediated chemotaxis and pro-inflammatory signaling in leukocytes
  • Enables research on membrane permeabilization mechanisms within multidrug-resistant bacterial assays
  • Useful for evaluating P2X7 receptor activation and NLRP3 inflammasome assembly

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ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY. The products offered on this website are intended solely for research and laboratory use. These products are not intended for human or animal consumption. They are not medicines or drugs and have not been evaluated or approved by the FDA to diagnose, treat, cure, or prevent any disease or medical condition. Any form of bodily introduction is strictly prohibited by law.

Description

LL-37 5mg (CAP-18) is a research-use-only laboratory material supplied for controlled research workflows, compound characterization, and analytical documentation review. It is manufactured under rigorous quality standards to support consistency, traceability, and batch-specific verification for qualified laboratory settings.

Key Product Details

  • Manufactured in accordance with rigorous quality standards to support ≥99% purity, as reflected in batch-specific documentation where available.
  • Every batch is third-party analyzed for identity, assay/potency, and sterility documentation where applicable.
  • Supplied in lyophilized powder form to help preserve stability throughout transport and storage.
  • Produced with lot-level traceability to support research documentation and laboratory recordkeeping.

Research Documentation Context

  • Supports compound characterization in controlled laboratory settings.
  • Provides batch-specific identity and purity documentation for research review.
  • Allows lot-level traceability across laboratory documentation workflows.
  • Supports comparison of product labeling, analytical documentation, and storage information during research planning.
  • Supports analytical review of peptide research materials within a strictly laboratory-focused context.

Specifications and Documentation

  • Certificate of Analysis: Available with batch-specific documentation where applicable.
  • Material Safety Data Sheet: Coming Soon.
  • Handling and Storage Instructions: Coming Soon.
  • Product Form: Lyophilized powder.
  • Purity Specification: ≥99% purity.
  • Intended Use: Laboratory research use only.

LL-37 5mg (CAP-18) is intended strictly for laboratory research use only. This product is not intended for human or animal consumption, therapeutic use, diagnostic use, clinical use, veterinary use, or as a food, drug, cosmetic, dietary supplement, or household product.

Additional information

CAS No.

154947-66-7

Purity

≥99%

Sequence

Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser

Molecular Formula

C205H340N60O53

Molecular Weight

4493.37 g/mol

Applications

Antimicrobial mechanisms research, biofilm disruption studies, wound healing and immunomodulation studies

Synthesis

Solid-phase synthesis

Format

Lyophilized powder

Solubility

Soluble in water or 1% acetic acid

Stability & Storage

Stable for up to 24 months at -20°C. After reconstitution, may be stored at 4°C for up to 4 weeks or at -20°C for up to 6 months.

Appearance

White lyophilized powder

Safety Information

Refer to provided MSDS

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Research Procurement Information

Buy LL-37 Online for Research | COA Documentation Guide

Researchers searching for buy LL-37 online should evaluate LL-37 as a research-use-only laboratory material, not a consumer product. For laboratory buyers, the key considerations are compound identity, LL-37 COA review, purity documentation, lot traceability, product labeling, storage information, and supplier evaluation. Pure Lab Peptides presents LL-37 5mg for controlled research procurement with batch-specific documentation, RUO positioning, lyophilized powder format, and an ≥99% purity claim.

Fast Answer: buy LL-37 online for laboratory research

Researchers can buy LL-37 online for laboratory research by reviewing RUO labeling, batch-specific COA documentation, purity data, identity information, storage guidance, and supplier transparency before selecting a source. Products discussed in this article are intended for laboratory research use only and are not intended for human or animal consumption.

What Does “Buy LL-37 Online” Mean in a Research Context?

The phrase “buy LL-37 online” is addressed here as laboratory research procurement intent, not personal-use intent. A qualified laboratory buyer is not evaluating LL-37 as a wellness product, supplement, medicine, or consumer-use peptide. The procurement task is to determine whether the listing, label, COA, product form, and supplier documentation support controlled research recordkeeping.

In that context, researchers should prioritize an LL-37 research-use-only listing that clearly separates procurement from use guidance. The appropriate review includes the product name, amount, RUO labeling, batch-specific COA, analytical method, lot number, storage notes, and documentation consistency. This is the same practical frame that technical procurement teams use when comparing any LL-37 research material: identity first, documentation second, and supplier transparency throughout.

LL-37 Research Material Overview

LL-37 is commonly described in scientific databases and literature as a 37-residue cathelicidin-derived peptide associated with the CAMP gene product and the hCAP-18 precursor. PubChem lists LL-37 with the molecular formula C205H340N60O53, while UniProt and NCBI Gene identify CAMP as the human cathelicidin antimicrobial peptide gene/protein context [1] [2] [3]. The commonly cited LL-37 sequence is Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser [1].

Published literature places LL-37 within cathelicidin and host-defense peptide research. A major review describes LL-37 as the only cathelicidin-derived antimicrobial peptide found in humans and discusses its amphipathic helical properties in research models [4]. Structural studies have examined LL-37 in lipid micelles, phospholipid membranes, dodecylphosphocholine micelles, and detergent membrane mimics, illustrating why identity and sequence confirmation matter for research procurement [5] [6] [7] [8].

Researchers should treat that literature as scientific context only. Reviews discuss LL-37 in antimicrobial peptide, innate pathway, structural, membrane-interaction, and peptide-fragment research areas [9] [10] [11] [12] [13]. Published LL-37 literature should not be interpreted as product-use guidance for RUO materials.

Why Researchers Search “Buy LL-37 Online”

Researchers often search “buy LL-37” when they need to compare RUO product availability, compound identity documentation, purity data, COA access, lot number matching, label consistency, storage and handling information, and supplier transparency. The search phrase is commercial, but the compliant procurement question is technical: does the supplier provide enough documentation for a laboratory to evaluate the material before adding it to research records?

For LL-37 supplier documentation, the buyer should review the product page, COA, analytical method, product form, and storage notes together. A product page alone is not a substitute for a batch-specific LL-37 COA. Likewise, an LL-37 COA should not be read in isolation from the label, lot number, and product description.

Research Procurement Checklist for LL-37

  • Verify that LL-37 is labeled for research use only.
  • Review the batch-specific certificate of analysis before procurement.
  • Confirm that the LL-37 COA includes identity and purity documentation.
  • Check whether HPLC, LC-MS, mass spectrometry, or another analytical method is listed.
  • Compare the product name, amount, lot number, and documentation for consistency.
  • Assess whether the supplier avoids dosing, therapeutic, consumer-use, or personal-use claims.
  • Document storage and handling information in laboratory records.
  • Evaluate whether lyophilized powder form matches the research workflow.
  • Confirm that the product is not marketed for human or animal consumption.

LL-37 Quality Signals to Review Before Buying Online

Research teams planning to buy LL-37 online for laboratory research should evaluate documentation quality before evaluating supplier convenience. HPLC is widely used for peptide separation and purification analysis, while mass spectrometry and LC-MS are common tools for peptide identity, mass, purity, and impurity review [14] [15] [16].

Evaluation Area What Researchers Should Review Why It Matters for RUO Procurement
RUO labeling Confirm the product is clearly labeled for research use only Helps separate research procurement from human-use positioning
COA availability Review the batch-specific certificate of analysis Supports lot-level documentation and quality review
Purity data Look for analytical support for the stated purity Helps evaluate material consistency
Identity testing Review HPLC, LC-MS, mass spectrometry, or related identity data Helps confirm the material matches the listed compound
Lot traceability Match lot numbers across product and documentation Supports research recordkeeping
Product form Confirm whether the material is supplied as lyophilized powder or another documented form Supports laboratory planning
Storage information Review storage and handling documentation Helps maintain material integrity in laboratory settings
Supplier language Confirm the supplier avoids dosing, therapeutic, or personal-use claims Supports research-use-only positioning

COA, Purity, and Identity Documentation

An LL-37 COA should be reviewed as a batch-level document, not as a generic marketing statement. Researchers should look for the compound name, lot number, test date, purity percentage, analytical method, identity confirmation, molecular weight or mass information, sequence reference, chromatogram or mass data, product form, and storage documentation. A purity percentage alone does not establish complete compound identity; researchers should evaluate purity, identity, method, lot number, and documentation together.

Analytical literature supports this combined approach. LC-MS workflows are used to characterize peptide-related impurities, and impurity profiling studies show why chromatographic and mass-based data can answer different documentation questions [17] [18]. Reference-standard work for synthetic peptides also emphasizes the value of multi-laboratory, mass-balance, and documentation-based approaches when assigning peptide quality attributes [19].

Regulatory analytical guidance is not a product endorsement, but it offers useful documentation principles. FDA and ICH guidance on analytical procedure validation and analytical procedure development discuss method suitability, spectroscopic data, lifecycle concepts, and science-based analytical procedure control [20] [21]. FDA bioanalytical guidance also reinforces that analytical methods should be documented for their intended purpose [22]. FDA RUO/IUO guidance, although specific to in vitro diagnostic products, illustrates the importance of intended-use labeling in separating research-use materials from regulated clinical positioning [23]. Stability guidance similarly highlights storage and stability documentation as part of quality review [24].

flowchart TD A[Receive product and COA] --> B{RUO labeling present?} B -- No --> C[Flag procurement gap] B -- Yes --> D{Lot number matches across label and COA?} D -- No --> E[Request batch-specific documentation] D -- Yes --> F{Identity supported by analytical method?} F -- No --> G[Request HPLC, LC-MS, or equivalent] F -- Yes --> H[Proceed to laboratory documentation and storage]

Research Literature Context

Published LL-37 literature is broad and should be summarized cautiously. Database records identify LL-37 as a defined peptide sequence and molecular entity, while review articles place it within cathelicidin and antimicrobial peptide research [1] [2] [4]. Structural papers have examined LL-37 conformation in membrane-like environments, including lipid micelles and membrane mimics, but those studies are not procurement instructions and do not define how an RUO material should be used [5] [7] [8].

The evidence landscape includes database-based identity records, in vitro and biophysical model studies, structural studies, antimicrobial peptide reviews, and analytical-method literature. Some published literature outside the scope of RUO product use discusses human-derived biology or clinical-adjacent contexts. Published clinical literature should not be interpreted as use guidance for RUO materials. For procurement purposes, the relevant takeaway is narrower: LL-37 identity, sequence, purity, and lot-level documentation must be evaluated before the material enters controlled laboratory records.

Evidence Landscape

Research Area What Literature Examines Evidence Type RUO Interpretation
Compound identity Molecular structure, sequence, formula, or classification Database / analytical Supports identification, not product-use claims
Pathway or category context Cathelicidin, host-defense peptide, membrane-model, or antimicrobial peptide research area Review / in vitro / structural / preclinical Useful for research context, not therapeutic claims
Analytical testing Purity, identity, and batch verification HPLC / LC-MS / mass spectrometry / COA Supports documentation review
Storage and stability Material form and handling considerations Laboratory documentation Supports research workflow planning

Claim Boundary Table

Research-Safe Statement Why It Is Acceptable Non-Compliant Version to Avoid
“LL-37 is discussed in published research related to cathelicidin and host-defense peptide models.” Describes literature context without making a product claim “LL-37 helps with a human outcome.”
“Researchers should review COA and identity data before procurement.” Focuses on documentation and quality review “Users should buy LL-37 for results.”
“Pure Lab Peptides supplies LL-37 as a research-use-only material.” Clarifies intended use “Pure Lab Peptides supplies LL-37 for therapy.”
“The phrase buy LL-37 online is addressed as research procurement intent.” Qualifies commercial search intent “Buy LL-37 online for personal use.”
“LL-37 identity testing should be reviewed alongside purity documentation.” Separates identity confirmation from a single purity number “A high purity percentage alone proves everything about LL-37.”

How Pure Lab Peptides Presents LL-37

Pure Lab Peptides presents LL-37 5mg as a research-use-only peptide material for qualified laboratory procurement. The product is listed as lyophilized powder with an ≥99% purity claim, batch-specific COA availability, RUO labeling, product page documentation, storage and handling review expectations, lot-level traceability, and supplier transparency. Researchers should review the Pure Lab Peptides LL-37 research-use-only product page for RUO labeling, product details, purity information, and batch-specific documentation.

For teams comparing LL-37 research material suppliers, the strongest documentation signals are consistency across the product page, label, COA, lot number, identity method, purity method, storage notes, and supplier language. A compliant supplier presentation should not convert LL-37 literature into dosing guidance, human-use positioning, or therapeutic claims.

Common Misunderstandings About Buying LL-37 Online

Misunderstanding: “Buy LL-37 online” means personal use

Buy LL-37 online should not be interpreted as personal-use guidance on this page. The phrase is addressed as laboratory procurement intent for qualified researchers reviewing RUO labeling, documentation, purity data, identity information, batch-specific COA records, and supplier transparency.

Misunderstanding: published literature equals product-use guidance

Published LL-37 literature can help researchers understand why the peptide appears in cathelicidin, structural, and antimicrobial peptide research. It does not define how an RUO product should be used, and it should not be converted into claims about outcomes, applications outside the laboratory, or regulated use.

Misunderstanding: purity percentage alone proves identity

LL-37 purity documentation is important, but a purity percentage alone does not establish complete identity. Researchers should review the compound name, sequence or molecular information, analytical method, mass or identity data, lot number, and batch-specific COA together before procurement.

Misunderstanding: COA documentation does not need to be batch-specific

A generic COA is less useful than a batch-specific LL-37 COA because laboratory records depend on lot-level matching. Technical procurement teams should compare the lot number on the product label, COA, and purchasing record so that documentation can be traced to the exact received material.

Misunderstanding: RUO labeling supports human or animal use

RUO labeling does the opposite. It clarifies that LL-37 is supplied as a laboratory research material and is not intended for human consumption, animal consumption, diagnostic use, clinical use, veterinary use, or personal-use experimentation.

Misunderstanding: supplier language can replace analytical documentation

Supplier descriptions may summarize product details, but they do not replace LL-37 identity testing, purity documentation, and batch-specific COA review. Researchers should evaluate claims against analytical records, method information, lot traceability, and consistent RUO labeling.

FAQs About Buying LL-37 Online for Research

Where can researchers buy LL-37 online for laboratory research?

Researchers can buy LL-37 online for laboratory research by reviewing RUO suppliers that provide clear labeling, batch-specific COA documentation, purity information, identity testing references, product form details, and lot-level traceability. Pure Lab Peptides lists LL-37 5mg on its RUO product page and broader research peptide collection.

What should researchers check before buying LL-37 online?

Before buying LL-37 online, researchers should check RUO labeling, the LL-37 COA, purity documentation, identity testing, product form, storage information, lot number consistency, and supplier language. The procurement review should confirm that the material is positioned only for controlled laboratory research and not for human or animal consumption.

Why does a COA matter when buying LL-37?

An LL-37 COA matters because it connects procurement to batch-level documentation. Researchers should review the compound name, lot number, purity value, analytical method, identity information, and test details. The COA supports recordkeeping, but it should be evaluated alongside label consistency, product form, and supplier documentation.

Is LL-37 intended for human or animal consumption?

No. LL-37 discussed here is a research-use-only material and is not intended for human or animal consumption. It is not presented as a medicine, supplement, clinical material, diagnostic material, veterinary product, or consumer-use item. Procurement should remain limited to qualified laboratory research contexts.

What does research use only mean for LL-37?

Research use only means LL-37 is supplied for laboratory research, analytical review, and controlled documentation workflows. RUO positioning requires clear separation from personal-use instructions, dosing language, clinical claims, animal-use directions, and outcome-based marketing. Researchers should document that intended use remains within institutional research controls.

How should published literature about LL-37 be interpreted?

Published literature about LL-37 should be interpreted as scientific context, not product-use guidance. Database, structural, in vitro, and review-based studies can inform compound identity and research background. They do not establish procurement suitability by themselves, and they should not be converted into claims about RUO material use.

Next Steps

Qualified researchers evaluating LL-37 should review product labeling, COA status, identity documentation, purity information, storage notes, and supplier transparency before selecting any research-use-only material. Review the LL-37 product page for RUO labeling, purity information, and available batch-specific documentation.

References

  1. National Center for Biotechnology Information. “LL-37.” PubChem Compound Database. 2026. https://pubchem.ncbi.nlm.nih.gov/compound/ll-37
  2. The UniProt Consortium. “CAMP – Cathelicidin antimicrobial peptide.” UniProtKB. 2026. https://www.uniprot.org/uniprotkb/P49913/entry
  3. National Center for Biotechnology Information. “CAMP cathelicidin antimicrobial peptide.” NCBI Gene. 2026. https://www.ncbi.nlm.nih.gov/gene/820
  4. Durr UHN, Sudheendra US, Ramamoorthy A. “LL-37, the only human member of the cathelicidin family of antimicrobial peptides.” Biochimica et Biophysica Acta – Biomembranes. 2006. https://doi.org/10.1016/j.bbamem.2006.03.030
  5. Wang G. “Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles.” Journal of Biological Chemistry. 2008. https://doi.org/10.1074/jbc.M805533200
  6. Oren Z, Lerman JC, Gudmundsson GH, Agerberth B, Shai Y. “Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes.” Biochemical Journal. 1999. https://doi.org/10.1042/BJ3410501
  7. Porcelli F, Verardi R, Shi L, Henzler-Wildman KA, Ramamoorthy A, Veglia G. “NMR structure of the cathelicidin-derived human antimicrobial peptide LL-37 in dodecylphosphocholine micelles.” Biochemistry. 2008. https://doi.org/10.1021/bi702036s
  8. Sancho-Vaello E, Gil-Carton D, François P, Bonetti EJ, Kreir M, Pothula KR, Kleinekathöfer U, Zeth K. “The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics.” Scientific Reports. 2020. https://doi.org/10.1038/s41598-020-74401-5
  9. Vandamme D, Landuyt B, Luyten W, Schoofs L. “A comprehensive summary of LL-37, the factotum human cathelicidin peptide.” Cellular Immunology. 2012. https://doi.org/10.1016/j.cellimm.2012.11.009
  10. Bhattacharjya S, Ramamoorthy A. “LL-37: Structures, Antimicrobial Activity, and Influence on Amyloid-Related Diseases.” Biomolecules. 2024. https://doi.org/10.3390/biom14030320
  11. Ridyard KE, Overhage J. “The Potential of Human Peptide LL-37 as an Antimicrobial and Anti-Biofilm Agent.” Antibiotics. 2021. https://doi.org/10.3390/antibiotics10060650
  12. Zasloff M. “Antimicrobial peptides of multicellular organisms.” Nature. 2002. https://doi.org/10.1038/415389a
  13. Yeaman MR, Yount NY. “Mechanisms of antimicrobial peptide action and resistance.” Pharmacological Reviews. 2003. https://doi.org/10.1124/pr.55.1.2
  14. Mant CT, Chen Y, Yan Z, Popa TV, Kovacs JM, Mills JB, Tripet BP, Hodges RS. “HPLC analysis and purification of peptides.” Methods in Molecular Biology. 2007. https://doi.org/10.1007/978-1-59745-430-8_1
  15. Prabhala BK, Mirza O, Hojrup P, Hansen PR. “Characterization of Synthetic Peptides by Mass Spectrometry.” Methods in Molecular Biology. 2015. https://pubmed.ncbi.nlm.nih.gov/26424265/
  16. Zhang G, Annan RS, Carr SA, Neubert TA. “Overview of peptide and protein analysis by mass spectrometry.” Current Protocols in Protein Science. 2010. https://pubmed.ncbi.nlm.nih.gov/21104985/
  17. Lian Z, Wang N, Tian Y, Huang L. “Characterization of Synthetic Peptide Therapeutics Using Liquid Chromatography-Mass Spectrometry: Challenges, Solutions, Pitfalls, and Future Perspectives.” Journal of the American Society for Mass Spectrometry. 2021. https://doi.org/10.1021/jasms.0c00479
  18. De Spiegeleer B, Vergote V, Pezeshki A, Peremans K, Burvenich CPG. “Impurity profiling quality control testing of synthetic peptides using liquid chromatography-photodiode array-fluorescence and liquid chromatography-electrospray ionization-mass spectrometry: the obestatin case.” Analytical Biochemistry. 2008. https://doi.org/10.1016/j.ab.2008.02.014
  19. McCarthy D, Han Y, Carrick K, Schmidt D, Workman W, Matejtschuk P, Duru C, Atouf F. “Reference Standards to Support Quality of Synthetic Peptide Therapeutics.” Pharmaceutical Research. 2023. https://doi.org/10.1007/s11095-023-03493-1
  20. U.S. Food and Drug Administration. “Q2(R2) Validation of Analytical Procedures.” FDA Guidance Document. 2024. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/q2r2-validation-analytical-procedures
  21. U.S. Food and Drug Administration. “Q14 Analytical Procedure Development.” FDA Guidance Document. 2024. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/q14-analytical-procedure-development
  22. U.S. Food and Drug Administration. “Bioanalytical Method Validation Guidance for Industry.” FDA Guidance Document. 2018. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/bioanalytical-method-validation-guidance-industry
  23. U.S. Food and Drug Administration. “Distribution of In Vitro Diagnostic Products Labeled for Research Use Only or Investigational Use Only.” FDA Guidance Document. 2013. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/distribution-in-vitro-diagnostic-products-labeled-research-use-only-or-investigational-use-only
  24. U.S. Food and Drug Administration. “Q1A(R2) Stability Testing of New Drug Substances and Products.” FDA Guidance Document. 2003. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/q1ar2-stability-testing-new-drug-substances-and-products

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